TAO: A Time-Aware Opportunistic Routing Protocol for Service Invocation in Intermittently Connected Networks

International audienceHandheld devices owned by nomadic people can form intermittently connected mobile ad hoc networks spontaneously. Such networks appear as an attractive solution for service providers, such as local authorities, in order to extend a pre-existing infrastructure-based network composed of several infostations so as to provide nomadic people with application services in a large scale area (e.g., a city). In such hybrid networks, intermittent connections are prevalent, and end-toend paths between clients and providers cannot be maintained all the time. Service provisioning thus remains a challenging problem today in these networks. In this paper, we propose a new time-aware opportunistic routing protocol called TAO. TAO is designed for service invocation in intermittently connected hybrid networks. This protocol makes it possible to select the best next message forwarder(s) among a set of neighbor nodes based on the dates of contacts of these nodes with infostations, and tends to implicitly estimate the distance separating these mobile nodes and the infostations. This paper gives a detailed description of this protocol supported with some simulation results

C3PO: A Network and Application Framework for Spontaneous and Ephemeral Social Networks

International audienceThe C3PO project promotes the development of new kind of social networks called Spontaneous and Ephemeral Social Networks (SESNs) dedicated to happenings such as cultural or sport events. SESNs rely on both opportunistic networks formed dynamically by the mobile devices of event attendees, and on an event-based communication model. Therefore, user can exchange digital contents with the other members of their SESNs, even without Internet access. This paper presents the framework developed in the C3PO project to provide network and application supports in such challenged networks. This framework exploits the different wireless interfaces of the mobile devices to interconnect them and to disseminate content through the resulting opportunistic network. At the application layer, this framework is composed of plugins that process locally the data stream to offer generic features, or to easily build applications dedicated to specific happenings

Specifications of Standards in Systems and Synthetic Biology: Status and Developments in 2016

Standards are essential to the advancement of science and technology. In systems and synthetic biology, numerous standards and associated tools have been developed over the last 16 years. This special issue of the Journal of Integrative Bioinformatics aims to support the exchange, distribution and archiving of these standards, as well as to provide centralised and easily citable access to them

C3PO: a Spontaneous and Ephemeral Social Networking Framework for a collaborative Creation and Publishing of Multimedia Contents

International audienceOnline social networks have been adopted by a large part of the population, and have become in few years essential communication means and a source of information for journalists. Nevertheless, these networks have some drawbacks that make people reluctant to use them, such as the impossibility to claim for ownership of data and to avoid commercial analysis of them, or the absence of collaborative tools to produce multimedia contents with a real editorial value. In this paper, we present a new kind of social networks, namely spontaneous and ephemeral social networks (SESNs). SESNs allow people to collaborate spontaneously in the production of multimedia documents so as to cover cultural and sport events

Specifications of Standards in Systems and Synthetic Biology: Status and Developments in 2016

Standards are essential to the advancement of science and technology. In systems and synthetic biology, numerous standards and associated tools have been developed over the last 16 years. This special issue of the Journal of Integrative Bioinformatics aims to support the exchange, distribution and archiving of these standards, as well as to provide centralised and easily citable access to them

Specifications of Standards in Systems and Synthetic Biology: Status and Developments in 2017

Standards are essential to the advancement of Systems and Synthetic Biology. COMBINE provides a formal body and a centralised platform to help develop and disseminate relevant standards and related resources. The regular special issue of the Journal of Integrative Bioinformatics aims to support the exchange, distribution and archiving of these standards by providing unified, easily citable access. This paper provides an overview of existing COMBINE standards and presents developments of the last year

Simulation of Postsynaptic Glutamate Receptors Reveals Critical Features of Glutamatergic Transmission

Activation of several subtypes of glutamate receptors contributes to changes in postsynaptic calcium concentration at hippocampal synapses, resulting in various types of changes in synaptic strength. Thus, while activation of NMDA receptors has been shown to be critical for long-term potentiation (LTP) and long term depression (LTD) of synaptic transmission, activation of metabotropic glutamate receptors (mGluRs) has been linked to either LTP or LTD. While it is generally admitted that dynamic changes in postsynaptic calcium concentration represent the critical elements to determine the direction and amplitude of the changes in synaptic strength, it has been difficult to quantitatively estimate the relative contribution of the different types of glutamate receptors to these changes under different experimental conditions. Here we present a detailed model of a postsynaptic glutamatergic synapse that incorporates ionotropic and mGluR type I receptors, and we use this model to determine the role of the different receptors to the dynamics of postsynaptic calcium with different patterns of presynaptic activation. Our modeling framework includes glutamate vesicular release and diffusion in the cleft and a glutamate transporter that modulates extracellular glutamate concentration. Our results indicate that the contribution of mGluRs to changes in postsynaptic calcium concentration is minimal under basal stimulation conditions and becomes apparent only at high frequency of stimulation. Furthermore, the location of mGluRs in the postsynaptic membrane is also a critical factor, as activation of distant receptors contributes significantly less to calcium dynamics than more centrally located ones. These results confirm the important role of glutamate transporters and of the localization of mGluRs in postsynaptic sites in their signaling properties, and further strengthen the notion that mGluR activation significantly contributes to postsynaptic calcium dynamics only following high-frequency stimulation. They also provide a new tool to analyze the interactions between metabotropic and ionotropic glutamate receptors

Altimetry for the future: Building on 25 years of progress

In 2018 we celebrated 25 years of development of radar altimetry, and the progress achieved by this methodology in the fields of global and coastal oceanography, hydrology, geodesy and cryospheric sciences. Many symbolic major events have celebrated these developments, e.g., in Venice, Italy, the 15th (2006) and 20th (2012) years of progress and more recently, in 2018, in Ponta Delgada, Portugal, 25 Years of Progress in Radar Altimetry. On this latter occasion it was decided to collect contributions of scientists, engineers and managers involved in the worldwide altimetry community to depict the state of altimetry and propose recommendations for the altimetry of the future. This paper summarizes contributions and recommendations that were collected and provides guidance for future mission design, research activities, and sustainable operational radar altimetry data exploitation. Recommendations provided are fundamental for optimizing further scientific and operational advances of oceanographic observations by altimetry, including requirements for spatial and temporal resolution of altimetric measurements, their accuracy and continuity. There are also new challenges and new openings mentioned in the paper that are particularly crucial for observations at higher latitudes, for coastal oceanography, for cryospheric studies and for hydrology. The paper starts with a general introduction followed by a section on Earth System Science including Ocean Dynamics, Sea Level, the Coastal Ocean, Hydrology, the Cryosphere and Polar Oceans and the ‘‘Green” Ocean, extending the frontier from biogeochemistry to marine ecology. Applications are described in a subsequent section, which covers Operational Oceanography, Weather, Hurricane Wave and Wind Forecasting, Climate projection. Instruments’ development and satellite missions’ evolutions are described in a fourth section. A fifth section covers the key observations that altimeters provide and their potential complements, from other Earth observation measurements to in situ data. Section 6 identifies the data and methods and provides some accuracy and resolution requirements for the wet tropospheric correction, the orbit and other geodetic requirements, the Mean Sea Surface, Geoid and Mean Dynamic Topography, Calibration and Validation, data accuracy, data access and handling (including the DUACS system). Section 7 brings a transversal view on scales, integration, artificial intelligence, and capacity building (education and training). Section 8 reviews the programmatic issues followed by a conclusion